Dim name As String = "marco"
        Dim cambia As String = "D'amico"
        Dim OleDbConn As System.Data.OleDb.OleDbConnection = New System.Data.OleDb.OleDbConnection
        OleDbConn.ConnectionString = String.Format("Provider=Microsoft.Jet.OLEDB.4.0;Data Source={0}mdb-database\nome.mdb;", Request.PhysicalApplicationPath)

        Dim Sql As String = "UPDATE news SET testo='" & cambia & "' WHERE nome ='" & name & "'"
        Dim Cmd As OleDb.OleDbCommand = OleDbConn.CreateCommand()
        Cmd.CommandText = Sql

        OleDbConn.Open()
        Cmd.ExecuteNonQuery()
        OleDbConn.Close()
        GridView1.DataBind()